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P0300 on the 2022 GMC Sierra

The bulletins listed name this code in NHTSA's summary, or are about the same components. A bulletin or a recall listed here may apply to the model year. None of it is a diagnosis.

Nobody has written a description of this code yet.

Bulletins for this model year that name P0300
23-NA-0022024-07-22. Service bulletin. This technical bulletin provides repair information to correct a customer concern of Charge Air Cooler (CAC) Icing, Check Engine Lamp Illuminated, Possible P0299, P2227, and/or P0300 DTCs Set.
PIP5628G2023-09-18. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
PIP5628F2023-05-15. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
PIP5628E2023-03-13. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
23-NA-0022023-02-08. Service bulletin. This technical bulletin provides repair information to correct a customer concern of Charge Air Cooler (CAC) Icing, Check Engine Lamp Illuminated, Possible P0299, P2227, and/or P0300 DTCs Set.
PIP58612022-08-15. Service bulletin. This Preliminary information communicates that a vehicle may exhibit a misfire condition resulting in misfire codes P0300-P0308. Upon diagnosis it may be discovered the lifter has come apart. It is recommended to replace the lifter guide and the four lifters.
PIP5628E2022-01-24. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D

7 on file from NHTSA, as of 2026-10-19. See them in the bulletin list. A bulletin lists model years: read the document for which vehicles it concerns.