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P0300 on the 2020 GMC Sierra

The bulletins listed name this code in NHTSA's summary, or are about the same components. A bulletin or a recall listed here may apply to the model year. None of it is a diagnosis.

Nobody has written a description of this code yet.

Bulletins for this model year that name P0300
23-NA-0022024-07-22. Service bulletin. This technical bulletin provides repair information to correct a customer concern of Charge Air Cooler (CAC) Icing, Check Engine Lamp Illuminated, Possible P0299, P2227, and/or P0300 DTCs Set.
23-NA-0432024-03-06. Service bulletin. This service bulletin provides a procedure to replace the valve lifter and guides to correct customer concerns of Poor Engine Performance, Engine Misfires, Malfunction Indicator Lamp (MIL) Illuminated - DTC P0300, P0301, P0302, P0303, P0304, P0305, P0306, P0307, P0308 Set.
PIP5628G2023-09-18. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
23-NA-0432023-05-16. Service bulletin. This service bulletin provides a procedure to replace the valve lifter and guides to correct customer concerns of Poor Engine Performance, Engine Misfires, Malfunction Indicator Lamp (MIL) Illuminated - DTC P0300, P0301, P0302, P0303, P0304, P0305, P0306, P0307, P0308 Set.
PIP5628F2023-05-15. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
23-NA-0432023-05-06. Service bulletin. This service bulletin provides a procedure to replace the valve lifter and guides to correct customer concerns of Poor Engine Performance, Engine Misfires, Malfunction Indicator Lamp (MIL) Illuminated - DTC P0300, P0301, P0302, P0303, P0304, P0305, P0306, P0307, P0308 Set.
PIP5776H2023-04-17. Service bulletin. This Preliminary information communicates that a vehicle may exhibit a misfire condition resulting in misfire codes P0300-P308. Upon diagnosis it may be discovered the lifter has come apart. It is recommended to replace the lifter guide and the four lifters.
PIP5628E2023-03-13. Service bulletin. This Preliminary information communicates information that will need to be provided to TAC to aid in diagnosing if a vehicle comes in with misfire and DTC Codes P0300 - P0308 and/or P050D
23-NA-0022023-02-08. Service bulletin. This technical bulletin provides repair information to correct a customer concern of Charge Air Cooler (CAC) Icing, Check Engine Lamp Illuminated, Possible P0299, P2227, and/or P0300 DTCs Set.
PIP5776G2022-05-16. Service bulletin. This Preliminary information communicates that a vehicle may exhibit a misfire condition resulting in misfire codes P0300-P308. Upon diagnosis it may be discovered the lifter has come apart. It is recommended to replace the lifter guide and the four lifters.

31 on file from NHTSA, as of 2026-10-19. See them in the bulletin list. A bulletin lists model years: read the document for which vehicles it concerns.